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Structure of 178388-79-9
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3-(1H-Imidazol-2-yl)propanoic acid features a polar imidazole ring linked via a methylene spacer to a carboxylic acid group, enabling dual functionality in hydrogen bonding and metal coordination. This scaffold integrates readily into bioactive molecules, offering enhanced solubility and targeted receptor interactions in medicinal chemistry applications.
3-(1H-Imidazol-2-yl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide conjugates. Its imidazole moiety provides strong hydrogen bonding capacity and moderate basicity, while the pendant carboxylic acid facilitates amide coupling and derivatization under standard conditions. The compound exhibits excellent bench stability and is readily purified by recrystallization or chromatography, making it well-suited for high-throughput screening campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: