Lot numbers can be found on the outside label of a product:
3-(3,4-Dimethoxyphenyl)-1-(3-hydroxyphenyl)propan-1-one
-
CAS No. 178445-83-5
- Cat. No. CS-0126652
- Purity≥98%
- MDL No.MFCD06245367
*For research and further manufacturing use only, not for direct human use.
Structure of 178445-83-5
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 178445-83-5
- Cat. No. CS-0126652
- Purity ≥98%
- MDL No. MFCD06245367
- Storage RT, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₇H₁₈O₄
- Molecular Weight 286.32
- Synonym(s) 3-(3,4-Dimethoxyphenyl)-1-(3-hydroxyphenyl)-1-propenone
- SMILES O=C(C1=CC=CC(O)=C1)CCC2=CC=C(OC)C(OC)=C2
Description
This chalcone derivative features a conjugated enone system flanked by electron-rich aromatic rings, enhancing its stability and reactivity in synthetic transformations. The 3,4-dimethoxyphenyl moiety imparts solubility and resistance to oxidation, while the phenolic hydroxyl group enables further derivatization or metal coordination. Designed for use in natural product synthesis and medicinal chemistry screening.
Application
3-(3,4-Dimethoxyphenyl)-1-(3-hydroxyphenyl)propan-1-one serves as a versatile scaffold for the synthesis of bioactive molecules, leveraging its conjugated enone system and multiple aromatic functional groups. The molecule enables efficient Michael additions, electrophilic substitutions, and transition-metal-catalyzed couplings due to its well-defined reactivity profile. Bench-stable and readily purified via crystallization, it functions as a key building block in natural product analogs and pharmaceutical intermediates requiring ortho-hydroxyl and methoxy-directed transformations.
Synthesis
-
Route1
-
In-stock
178445-80-2 - ~87%
-
In-stock
178445-83-5
References
-
ARIAD PHARMACEUTICALS, INCORPORATED; LI, Feng; WANG, Yihan Patent: WO2012/103279 A2, 2012 ; Location in patent: Page/Page column 7-8 ;
-
-
Route2
-
In-stock
121-71-1 - ~%
-
In-stock
178445-83-5
References
-
ARIAD PHARMACEUTICALS, INCORPORATED; LI, Feng; WANG, Yihan Patent: WO2012/103279 A2, 2012 ;
-
-
Route3
-
120-14-9 - ~%
-
In-stock
178445-83-5
References
-
ARIAD PHARMACEUTICALS, INCORPORATED; LI, Feng; WANG, Yihan Patent: WO2012/103279 A2, 2012 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 55.76
- LogP 3.2249
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 6
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 178445-83-5 sigma178445-83-5 manufacturer178445-83-5 price178445-83-5 structure178445-83-5 SDSbuy 178445-83-5178445-83-5 supplier178445-83-5 uses178445-83-5 molecular weightprice of 178445-83-5178445-83-5 chemical name formula of 178445-83-5