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CS-W001157 4
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Azide-PEG3-Tos

  • CAS No. 178685-33-1

  • Cat. No. CS-0114308
  • Purity≥97%
  • MDL No.MFCD18433411

*For research and further manufacturing use only, not for direct human use.

Azide-PEG3-Tos|CS-0114308

Structure of 178685-33-1

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General Information

  • CAS No. 178685-33-1
  • Cat. No. CS-0114308
  • Purity ≥97%
  • MDL No. MFCD18433411
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉N₃O₅S
  • Molecular Weight 329.37
  • Synonym(s) None
  • SMILES [N-]=[N+]=NCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O

Description

Azide-PEG3-Tos features a trifunctional PEG3 spacer linking an azide group to a tosylate leaving group, enabling efficient bioorthogonal conjugation and orthogonal functionalization. This bifunctional scaffold facilitates site-specific labeling in complex biological systems under mild conditions.

Application

Azide-PEG3-Tos serves as a versatile bifunctional linker for bioconjugation and polymer chemistry, combining the stability of a tosylate leaving group with the orthogonal reactivity of an azide. The PEG3 spacer provides enhanced solubility and reduced steric hindrance, enabling efficient coupling in aqueous or mixed solvents. Its bench-stable nature facilitates straightforward handling and purification, making it ideal for constructing functionalized scaffolds in drug delivery systems and chemical biology applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   110.59
  • LogP   2.04382
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   11

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