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Structure of 178813-78-0
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2,6-Dichloro-3-fluorobenzoic acid features a highly electron-deficient aromatic core stabilized by orthogonal halogen substituents. This configuration enhances its utility in coupling reactions and as a building block for bioactive heterocycles. The carboxylic acid group enables direct functionalization under standard conditions.
2,6-Dichloro-3-fluorobenzoic acid serves as a valuable building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-dichloro and meta-fluoro substitution pattern enables selective functionalization in late-stage derivatization, offering enhanced metabolic stability and favorable lipophilicity. The carboxylic acid group facilitates direct coupling reactions, amidation, or esterification under standard conditions, with excellent bench stability and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: