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Structure of 1801425-40-0
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6-Chloro-8-iodo-9H-purine is a halogenated purine scaffold featuring strategically positioned chlorine and iodine substituents at the 6- and 8-positions, respectively. This electronic and steric profile enables direct incorporation into transition-metal-catalyzed coupling reactions, facilitating rapid access to complex nucleoside analogs and functionalized purine architectures under standard conditions.
6-Chloro-8-iodo-9H-purine serves as a versatile building block for the synthesis of purine-based scaffolds in medicinal chemistry and catalytic cross-coupling applications. The strategically positioned chloro and iodo groups enable sequential functionalization via palladium-catalyzed coupling reactions, offering orthogonal reactivity for diversification. Bench-stable and readily purified by crystallization, it facilitates efficient access to complex heterocyclic architectures with high regiocontrol.
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Lot numbers can be found on the outside label of a product: