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Structure of 18027-45-7
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Phenyltris(dimethylsiloxy)silane serves as a stable, moisture-tolerant silylating agent featuring a phenyl group and three dimethylsiloxy substituents. This bulky, bench-stable reagent facilitates selective protection of alcohols and amines in complex molecular architectures. The silicon center enables efficient coupling under mild conditions, while the electron-donating siloxy groups enhance reactivity without compromising handling safety.
Phenyltris(dimethylsiloxy)silane serves as a stable, bench-ready silyl transfer reagent enabling efficient protection of alcohols and selective silylation of sensitive functional groups. Its high functional group tolerance and compatibility with standard reaction conditions facilitate reliable downstream transformations in complex molecule synthesis. The trimethylsilyl-like reactivity profile is achieved without the volatility or moisture sensitivity associated with traditional TMS reagents, making it ideal for scalable, reproducible protocols in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: