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Structure of 1803598-27-7
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Sodium 2-(pyridin-2-yl)propanoate features a pyridine ring directly attached to a chiral α-carbon, enabling robust coordination in transition metal catalysis. This bench-stable salt delivers enhanced solubility in polar solvents, facilitating efficient coupling reactions under mild conditions. The carboxylate moiety serves as a strong ligand anchor, while the pyridyl group provides directional electronic stabilization.
Sodium 2-(pyridin-2-yl)propanoate serves as a versatile building block in medicinal chemistry, enabling efficient access to chiral pyridylpropanoic acid derivatives. Its stability under ambient conditions and compatibility with standard coupling reactions facilitate straightforward incorporation into complex molecular architectures. The carboxylate functionality supports direct derivatization or metalation for further functionalization, while the ortho-pyridyl group provides a handle for coordination or cyclization strategies. Functions effectively in both solution-phase synthesis and solid-phase workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319-H335
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Precautionary Statements : P261-P302+P352
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Lot numbers can be found on the outside label of a product: