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*For research and further manufacturing use only, not for direct human use.
Structure of 180464-87-3
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Methyl 3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxylate features a rigid, cage-like bicyclo[1.1.1]pentane core that imparts exceptional stability and low conformational flexibility. The pendant hydroxymethyl group enables straightforward derivatization, while the ester functionality supports efficient downstream transformations. This scaffold delivers enhanced metabolic resistance and improved membrane permeability in bioactive molecule design.
Methyl 3-(hydroxymethyl)bicyclo[1.1.1]pentane-1-carboxylate serves as a versatile building block for the synthesis of constrained bioactive molecules, leveraging the rigid bicyclo[1.1.1]pentane core to enhance metabolic stability and modulate physicochemical properties. The pendant hydroxymethyl group enables straightforward derivatization via oxidation, protection, or coupling reactions, while the ester functionality supports further transformations. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient integration into medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: