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Structure of 1805192-57-7
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2-Bromo-5-fluoro-4-methylpyrimidine features a strategically positioned bromine and fluorine substitution pattern that enables selective cross-coupling reactions. The methyl group enhances solubility and electronic modulation, while the halogen framework supports efficient palladium-catalyzed transformations. This pyrimidine derivative serves as a key building block in medicinal chemistry and agrochemical synthesis.
2-Bromo-5-fluoro-4-methylpyrimidine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen reactivity. The bromo group facilitates efficient C–C bond formation, while the fluorine and methyl substituents offer predictable electronic tuning and steric control. Its bench-stable crystalline form simplifies handling and purification, making it ideal for constructing heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: