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Structure of 1805222-04-1
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This fluorinated pyridine scaffold integrates a bromine electrophile and a difluoromethyl group, enabling direct functionalization in cross-coupling reactions. The electron-deficient ring enhances reactivity in palladium-catalyzed transformations, while the difluoromethyl moiety imparts metabolic stability and modulates electronic properties for medicinal chemistry applications.
5-Bromo-3-(difluoromethyl)-2-fluoropyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine and fluorine substituents. The difluoromethyl group enhances metabolic stability and modulates lipophilicity, while the pyridine core provides a rigid scaffold for targeted molecular design. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient synthesis of complex heterocyclic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: