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Structure of 180530-15-8
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N-(5-Bromopyrimidin-2-yl)acetamide features a brominated pyrimidine core paired with a labile acetamide group, enabling direct functionalization in heterocyclic synthesis. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents, offering robust stability under standard conditions and compatibility with palladium-catalyzed coupling reactions.
N-(5-Bromopyrimidin-2-yl)acetamide serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds through palladium-catalyzed cross-coupling reactions. The bromine atom facilitates Suzuki, Stille, and Negishi couplings, while the acetamide group provides moderate stability and favorable solubility for downstream transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing functionalized heterocycles in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: