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CS-W001157 4
Total: USD 88.00

2,2'-Biphenol

  • CAS No. 1806-29-7

  • Cat. No. CS-W016899
  • Molecule weight186.21
  • Purity≥98%
  • MDL No.MFCD00002210

*For research and further manufacturing use only, not for direct human use.

2,2'-Biphenol|CS-W016899

Structure of 1806-29-7

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General Information

  • CAS No. 1806-29-7
  • Cat. No. CS-W016899
  • Purity ≥98%
  • MDL No. MFCD00002210
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₀O₂
  • Molecular Weight 186.21
  • Synonym(s) o,o'-Biphenol
  • SMILES OC1=C(C2=CC=CC=C2O)C=CC=C1

Description

2,2'-Biphenol serves as a rigid, electron-rich scaffold for constructing functionalized aromatic systems. This ortho-linked biphenyl derivative exhibits enhanced stability and facilitates precise spatial control in ligand design, enabling efficient coordination in catalytic applications.

Application

2,2'-Biphenol serves as a versatile building block in organic synthesis, enabling the construction of chiral ligands and functionalized heterocycles. Its ortho-hydroxyl groups facilitate metal coordination and participate in directed ortho-metalation, while exhibiting sufficient bench stability for routine handling. The molecule functions effectively in coupling reactions and acts as a scaffold for pharmaceutical intermediates requiring rigid, aromatic frameworks with defined polarity.

Synthesis

  • Route1
    • null|null
      1196786-63-6
    • ~96%
    • In-stock
      2,2'-Biphenol|CS-W016899
      1806-29-7

    References

    • Yan, Hailong; Oh, Joong-Suk; Song, Choong Eui Organic and Biomolecular Chemistry, 2011 , vol. 9, # 23 p. 8119 - 8121
  • Route2
    • null|null
      95-56-7
    • ~63%
    • In-stock
      2,2'-Biphenol|CS-W016899
      1806-29-7

    References

    • Lourak, Mouhsine; Vanderesse, Regis; Fort, Yves; Caubere, Paul Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4840 - 4844
  • Route3
    • null|null
      1227735-80-9
    • ~99%
    • In-stock
      2,2'-Biphenol|CS-W016899
      1806-29-7

    References

    • Huang, Chunhui; Gevorgyan, Vladimir Organic Letters, 2010 , vol. 12, # 10 p. 2442 - 2445

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   2.7648
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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