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Structure of 1806680-93-2
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Methyl 3-(3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl)-3-oxopropanoate features a sterically hindered pyrazole core linked to a β-keto ester moiety, enabling direct integration into heterocyclic coupling reactions. The difluoromethyl group enhances metabolic stability and modulates electronic properties, while the bench-stable enolizable ketone facilitates efficient functionalization under mild conditions.
Methyl 3-(3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl)-3-oxopropanoate serves as a versatile building block for constructing pyrazole-based heterocycles and bioactive scaffolds. The α,β-unsaturated ester functionality enables efficient Michael additions and condensation reactions, while the difluoromethyl group imparts enhanced metabolic stability and modulates electronic properties. Bench-stable and readily purified by flash chromatography, it functions effectively in multistep syntheses targeting medicinal chemistry leads and agrochemical intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: