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Structure of 1806763-56-3
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6-Bromo-2-(difluoromethyl)-3-fluoropyridine features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties. This fluorinated pyridine scaffold integrates readily into medicinal chemistry workflows, offering improved lipophilicity and bioavailability. The bromo substituent enables facile cross-coupling transformations under standard conditions.
6-Bromo-2-(difluoromethyl)-3-fluoropyridine serves as a versatile building block in medicinal chemistry, enabling direct incorporation of fluorinated and brominated motifs into bioactive scaffolds. Its ortho-bromine and trifluoromethyl-like difluoromethyl group facilitate palladium-catalyzed cross-coupling reactions and offer enhanced metabolic stability. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, making it ideal for the construction of complex heterocycles and API candidates requiring precise fluorination patterns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: