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Structure of 1806766-03-9
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3-(Difluoromethyl)-2(1H)-pyridinone features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties. This electron-deficient pyridinone scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in medicinal chemistry. Its bench-stable nature supports reliable handling and incorporation under standard conditions.
3-(Difluoromethyl)-2(1H)-pyridinone serves as a versatile building block in medicinal chemistry, enabling direct introduction of a difluoromethyl group into bioactive scaffolds. Its pyridinone core offers enhanced metabolic stability and favorable polarity, while the difluoromethyl substituent imparts strong electron-withdrawing character and improved membrane permeability. The compound exhibits bench stability and compatibility with standard coupling reactions, facilitating downstream functionalization in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: