Propargyl-PEG2-Boc

Name: Propargyl-PEG2-Boc
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1807503-80-5
Cat. No. CS-0109367
Purity≥95%
MDL No.MFCD28505565

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

Propargyl-PEG2-Boc features a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition, flanked by a short PEG2 spacer and a Boc-protected amine. This combination enables selective bioconjugation while maintaining solubility and stability under standard conditions.

Application

Propargyl-PEG2-Boc serves as a versatile bifunctional building block for conjugation and protection strategies in synthetic chemistry. The terminal alkyne enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the Boc group provides reliable protection of primary amines under mild acidic conditions. Its PEG2 spacer enhances solubility and reduces aggregation, facilitating purification and downstream applications in peptide modification, probe synthesis, and macrocyclic scaffold construction.

General Information

CAS No. 1807503-80-5
Cat. No. CS-0109367
Purity ≥95%
MDL No. MFCD28505565
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₀O₄
Molecular Weight 228.28
Synonym(s) None
SMILES O=C(OC(C)(C)C)CCOCCOCC#C

Computational Chemistry Data

TPSA 44.76
LogP 1.3846
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 7

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Other Classifications

Life Science Linker Alkyne PEG

Life Science Linker Propargyl PEG

Life Science Click Chemistry Reagents

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry PEG Azides/Alkynes

Chemical Biology Conjugation Chemistry/Click Chemistry PEG Azides/Alkynes

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

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Propargyl-PEG2-Boc

CAS No. 1807503-80-5

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