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Bromoacetamido-PEG4-C2-Boc

  • CAS No. 1807521-00-1

  • Cat. No. CS-0108852
  • Purity≥98%
  • MDL No.MFCD28505519

*For research and further manufacturing use only, not for direct human use.

Bromoacetamido-PEG4-C2-Boc|CS-0108852

Structure of 1807521-00-1

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General Information

  • CAS No. 1807521-00-1
  • Cat. No. CS-0108852
  • Purity ≥98%
  • MDL No. MFCD28505519
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₃₂BrNO₇
  • Molecular Weight 442.34
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCOCCNC(CBr)=O

Description

Bromoacetamido-PEG4-C2-Boc features a bromoacetamide handle flanked by a PEG4 spacer and a C2 linker, terminating in a Boc-protected amine. This bifunctional reagent enables site-specific conjugation under mild conditions, with the protected amine allowing for subsequent deprotection and functionalization. The PEG4 segment enhances solubility and reduces non-specific binding in aqueous environments.

Application

Bromoacetamido-PEG4-C2-Boc serves as a versatile bifunctional linker for bioconjugation and peptide synthesis, enabling site-specific attachment via its bromoacetamide group while the Boc-protected amine allows for subsequent deprotection and functionalization. The PEG4 spacer enhances solubility and reduces steric hindrance, facilitating efficient conjugation in aqueous environments. Its bench-stable, crystalline form simplifies handling and purification, making it well-suited for scalable synthesis of targeted protein-drug conjugates and labeled biomolecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   92.32
  • LogP   1.2957
  • H_Acceptors   7
  • H_Donors   1
  • Rotatable_Bonds   16

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