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CS-W001157 4
Total: USD 88.00

4,6-Dimethylpicolinic acid

  • CAS No. 18088-10-3

  • Cat. No. CS-0204920
  • Purity≥98%
  • MDL No.MFCD04113826
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,6-Dimethylpicolinic acid|CS-0204920

Structure of 18088-10-3

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Description

4,6-Dimethylpicolinic acid offers a sterically hindered, electron-rich pyridine scaffold ideal for coordinating transition metals in catalytic systems. The ortho-methyl groups enhance stability and modulate reactivity, while the carboxylic acid functionality enables direct coupling or derivatization. This robust building block facilitates efficient access to functionalized heterocycles under standard conditions.

Application

4,6-Dimethylpicolinic acid serves as a versatile building block in medicinal chemistry and catalysis, offering enhanced steric and electronic properties due to its methyl-substituted pyridine core. Its carboxylic acid functionality enables direct coupling reactions, while the ortho-methyl groups provide metabolic stability and modulate solubility. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for use in API synthesis and ligand development.

General Information

  • CAS No. 18088-10-3
  • Cat. No. CS-0204920
  • Purity ≥98%
  • MDL No. MFCD04113826
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI)
  • SMILES O=C(O)C=1N=C(C=C(C1)C)C

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.39664
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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