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CS-W001157 4
Total: USD 88.00

1,3-Dicyclohexyl-1H-imidazol-3-ium chloride

  • CAS No. 181422-72-0

  • Cat. No. CS-W012403
  • Purity≥97%
  • MDL No.MFCD04973309

*For research and further manufacturing use only, not for direct human use.

1,3-Dicyclohexyl-1H-imidazol-3-ium chloride|CS-W012403

Structure of 181422-72-0

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General Information

  • CAS No. 181422-72-0
  • Cat. No. CS-W012403
  • Purity ≥97%
  • MDL No. MFCD04973309
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₅ClN₂
  • Molecular Weight 268.83
  • Synonym(s) IcHex·HCl
  • SMILES [N+]1(C2CCCCC2)=CN(C3CCCCC3)C=C1.[Cl-]

Description

1,3-Dicyclohexyl-1H-imidazol-3-ium chloride is a bench-stable, moisture-tolerant imidazolium salt featuring two bulky cyclohexyl groups that enhance solubility in organic media. This structure imparts high thermal stability and facilitates use in catalytic systems requiring non-nucleophilic counterions. The cation serves as an effective phase-transfer agent and stabilizing scaffold in asymmetric synthesis.

Application

1,3-Dicyclohexyl-1H-imidazol-3-ium chloride serves as a stable, bench-friendly N-heterocyclic carbene precursor that facilitates efficient coupling reactions in synthetic organic chemistry. Its robustness enables reliable use in transition-metal-catalyzed transformations and C–H activation processes, with excellent functional group tolerance and ease of handling. The chloride counterion supports straightforward purification and compatibility with diverse reaction conditions, making it a practical choice for constructing complex molecular architectures in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   8.81
  • LogP   0.79
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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