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CS-W001157 4
Total: USD 88.00

(Chloromethyl)triisopropoxysilane

  • CAS No. 18162-82-8

  • Cat. No. CS-0154179
  • Purity≥98%
  • MDL No.MFCD05664343
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(Chloromethyl)triisopropoxysilane|CS-0154179

Structure of 18162-82-8

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Description

(Chloromethyl)triisopropoxysilane delivers a reactive chloromethyl group tethered to a triisopropoxysilyl moiety, enabling direct functionalization of surfaces and polymers. This moisture-tolerant silane integrates seamlessly into coupling reactions, offering stable anchoring through robust Si–O–Si linkages. The bulky isopropoxy groups enhance solubility and reduce hydrolytic cross-linking, facilitating controlled grafting under ambient conditions.

Application

(Chloromethyl)triisopropoxysilane serves as a stable, bench-ready silyl-protected chloromethyl building block, enabling efficient introduction of reactive CH₂Cl groups under mild conditions. Its triisopropoxysilyl moiety provides excellent functional group tolerance and facilitates straightforward deprotection with fluoride sources, making it ideal for iterative synthesis of complex molecules, including heterocyclic scaffolds and pharmaceutical intermediates.

General Information

  • CAS No. 18162-82-8
  • Cat. No. CS-0154179
  • Purity ≥98%
  • MDL No. MFCD05664343
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₃ClO₃Si
  • Molecular Weight 254.83
  • Synonym(s) Chloromethyltriisopropoxysilane96
  • SMILES CC(C)O[Si](CCl)(OC(C)C)OC(C)C

Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.9783
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   7

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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