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Structure of 18163-47-8
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1-Iodo-2-(trimethylsilyl)acetylene may be used to investigate the reactivity of diamagnetic cobalt(I) complex, Tol-BDI((2-pp)2)Co [Tol-BDI((2-pp)2)H = 2-(4-tolyl)-1,3-bis(2-isopropylpyridyl)propenediimine]. It may be used for the synthesis of 1-(4-trimethylsilanylbuta-1,3-diynyl)pyrene, via Pd-coupling with 1-iodo-2-trimethylsilylacetylene.
(Iodoethynyl)trimethylsilane serves as a reliable, bench-stable building block for Sonogashira coupling reactions and alkyne functionalization. Its terminal alkyne moiety enables efficient C–C bond formation under mild palladium catalysis, while the trimethylsilyl group provides enhanced stability and facilitates selective deprotection. This reagent functions effectively in diverse synthetic contexts, including heterocycle construction and late-stage functionalization, offering predictable reactivity and straightforward purification.
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GHS Pictogram :
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GHS No : GHS02,GHS07,GHS08
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H302+H312+H332-H317-H334-H361
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P272-P280-P304+P340-P330-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: