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Structure of 1820569-46-7
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This difluoromethyl-substituted cyclopropane carboxylic acid features a strained, rigid scaffold with enhanced metabolic stability. The electron-withdrawing difluoromethyl group imparts strong acidity and modulates lipophilicity, enabling effective incorporation into bioactive molecules. Designed for medicinal chemistry applications, this building block facilitates the development of novel therapeutics through improved pharmacokinetic profiles.
(1S,2S)-2-(Difluoromethyl)cyclopropanecarboxylic acid serves as a valuable chiral building block in medicinal chemistry, enabling the introduction of a rigid, electron-deficient difluoromethylcyclopropane motif. Its stability under standard synthetic conditions and compatibility with common functional groups facilitate incorporation into bioactive scaffolds, particularly in CNS-targeted compounds and enzyme inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: