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Structure of 1820685-06-0
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tert-Butyl 6-(chloromethyl)-1H-indole-1-carboxylate features a chloromethyl group at the 6-position of the indole ring, enabling direct functionalization in late-stage diversification. The tert-butyl ester provides stability and ease of removal under mild acidic conditions, while the electron-rich indole scaffold supports further derivatization in synthetic and medicinal chemistry workflows.
tert-Butyl 6-(chloromethyl)-1H-indole-1-carboxylate serves as a versatile building block for indole-based scaffolds, enabling efficient functionalization at the 6-position. The chloromethyl group facilitates nucleophilic substitution reactions, including aminolysis and thiolation, while the tert-butyl ester is compatible with standard deprotection protocols. Its bench-stable nature and ease of purification make it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331-H341
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: