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Structure of 182344-15-6
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This boronate moiety features a sterically shielded phenolic hydroxyl group, enhancing stability and resistance to oxidation. The ortho-tert-butyl substituents provide significant steric protection, enabling reliable coupling in Suzuki-Miyaura reactions under standard conditions. Ideal for constructing complex architectures with high functional group tolerance.
(3,5-Di-tert-butyl-4-hydroxyphenyl)boronic acid serves as a stable, sterically hindered phenolic boronic acid that facilitates Suzuki-Miyaura coupling under mild conditions. Its ortho-di-tert-butyl substitution enhances bench stability and minimizes protodeboronation, enabling reliable cross-coupling with aryl halides and pseudohalides. The hydroxyl group provides a handle for downstream functionalization, making this reagent valuable in constructing hindered biaryl architectures and antioxidant scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: