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Structure of 183208-22-2
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5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine features a brominated pyrrolopyridine core with a methyl group at the nitrogen, enabling direct functionalization in cross-coupling reactions. The electron-deficient heterocycle integrates efficiently into complex scaffolds, offering high reactivity under standard conditions with minimal decomposition. This bench-stable compound serves as a key building block for pharmaceutical intermediates and advanced materials.
5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine serves as a versatile building block for the synthesis of biologically active heterocycles, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the methylated pyrrolopyridine core provides structural rigidity and enhanced metabolic stability. This compound exhibits excellent bench stability and simplifies purification, making it well-suited for medicinal chemistry campaigns and process development in API synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: