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CS-W001157 4
Total: USD 88.00

2-Chloro 3-methylpyridine

  • CAS No. 18368-76-8

  • Cat. No. CS-W011138
  • Purity≥98%
  • MDL No.MFCD00234177

*For research and further manufacturing use only, not for direct human use.

2-Chloro 3-methylpyridine|CS-W011138

Structure of 18368-76-8

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General Information

  • CAS No. 18368-76-8
  • Cat. No. CS-W011138
  • Purity ≥98%
  • MDL No. MFCD00234177
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆ClN
  • Molecular Weight None
  • Synonym(s) 2-CHLORO-3-PICOLINE 2-CHLORO-3-METHYLPYRIDINE
  • SMILES C1=CC=NC(=C1C)Cl

Description

3-Chlorobenzylmagnesium chloride is used as pharmaceutical intermediate.

Application

2-Chloro-3-methylpyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive halogen site. The methyl group provides a handle for further functionalization, while the pyridine core offers favorable electronic properties and metabolic stability. Bench-stable and readily purified by distillation, it functions effectively in SNAr reactions and transition-metal-mediated transformations.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.04342
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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