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Structure of 184150-96-7
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Methyl 2-methyl-1H-indole-6-carboxylate features a sterically hindered indole core with a methyl group at the 2-position and a carboxylate ester at the 6-position. This configuration enhances solubility in organic solvents while maintaining stability under standard bench conditions. The molecule serves as a key scaffold for synthesizing bioactive indole derivatives, particularly in medicinal chemistry and natural product analogs.
Methyl 2-methyl-1H-indole-6-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted indole scaffolds relevant to medicinal chemistry. The methyl ester group facilitates straightforward derivatization via hydrolysis or nucleophilic substitution, while the 2-methyl substituent enhances regioselectivity in electrophilic aromatic substitution. Its bench-stable nature and compatibility with standard coupling reactions make it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: