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Structure of 18437-68-8
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tert-Butyl (4-methoxyphenyl)carbamate serves as a robust protecting group for primary amines, offering enhanced stability under acidic conditions. The para-methoxy substituent imparts electron-donating character, improving compatibility with diverse reaction sequences. This derivative facilitates selective deprotection in mild conditions, enabling efficient synthesis of functionalized arylamines.
tert-Butyl (4-methoxyphenyl)carbamate serves as a stable, bench-ready amino protecting group for primary amines, enabling efficient N-alkylation and coupling reactions. Its orthogonality to standard deprotection conditions facilitates sequential functionalization in complex molecule synthesis. The 4-methoxyphenyl moiety enhances solubility and simplifies purification via chromatography, while the tert-butyl carbamate fragment is readily removed under mild acidic conditions, making it ideal for peptide and medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: