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Structure of 1844839-22-0
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4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde delivers a boronate handle flanked by an electron-deficient fluoro substituent and a reactive aldehyde group. This combination enables efficient Suzuki-Miyaura coupling and orthogonal functionalization under standard conditions. The tetramethyl-substituted dioxaborolane enhances stability and shelf life.
4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The aldehyde functionality enables direct derivatization via oxidation, reduction, or nucleophilic addition, while the tetramethylboronate group exhibits excellent stability, mild handling requirements, and broad functional group tolerance. This compound facilitates efficient construction of substituted aryl aldehydes and heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: