3-Bromo-2-chloro-6-picoline

Name: 3-Bromo-2-chloro-6-picoline
Brand: ChemScene
Availability: InStock
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CAS No. 185017-72-5
Cat. No. CS-W015299
Purity≥97%
MDL No.MFCD03095218

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

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Structure of 185017-72-5

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Description

3-Bromo-2-chloro-6-picoline features a trifunctional pyridine core with bromo, chloro, and methyl groups positioned for orthogonal reactivity. This electron-deficient heterocycle enables selective cross-coupling and functionalization under palladium catalysis, offering high stability and compatibility with diverse reaction conditions.

Application

3-Bromo-2-chloro-6-picoline serves as a versatile heterocyclic building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient access to substituted pyridine scaffolds. Its orthogonal halogenation pattern facilitates selective functionalization, while the molecule exhibits excellent bench stability and compatibility with standard synthetic protocols.

General Information

CAS No. 185017-72-5
Cat. No. CS-W015299
Purity ≥97%
MDL No. MFCD03095218
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅BrClN
Molecular Weight 206.47
Synonym(s) 3-Bromo-2-chloro-6-methylpyridine
SMILES C1=CC(=NC(=C1Br)Cl)C

Computational Chemistry Data

TPSA 12.89
LogP 2.80592
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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3-Bromo-2-chloro-6-picoline

CAS No. 185017-72-5

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