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Structure of 18502-05-1
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2-(1H-Imidazol-4-yl)acetonitrile features a polar nitrile group flanked by a bioactive imidazole ring, enabling robust integration into pharmaceutical scaffolds. This bench-stable, moisture-tolerant building block facilitates efficient coupling in late-stage functionalization and transition-metal-catalyzed transformations.
2-(1H-Imidazol-4-yl)acetonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to imidazole-containing scaffolds via standard functional group transformations. Its nitrile group facilitates nucleophilic additions and cyclizations, while the imidazole moiety provides hydrogen-bonding capacity and metabolic stability. The compound exhibits good bench stability and is compatible with common reaction conditions, making it a practical choice for synthesizing bioactive heterocycles and peptide extensions.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301+H311+H331-H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501
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Lot numbers can be found on the outside label of a product: