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CS-W001157 4
Total: USD 88.00

1,1,2-Tris(tert-butoxycarbonyl)hydrazine

  • CAS No. 185456-26-2

  • Cat. No. CS-M3672
  • Purity≥97%
  • MDL No.MFCD04973130

*For research and further manufacturing use only, not for direct human use.

1,1,2-Tris(tert-butoxycarbonyl)hydrazine|CS-M3672

Structure of 185456-26-2

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General Information

  • CAS No. 185456-26-2
  • Cat. No. CS-M3672
  • Purity ≥97%
  • MDL No. MFCD04973130
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₈N₂O₆
  • Molecular Weight 332.39
  • Synonym(s) Hydrazinetricarboxylic acid, tris(1,1-dimethylethyl) ester; tri-tert-Butyl hydrazine-1,1,2-tricarboxylate
  • SMILES O=C(NN(C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)OC(C)(C)C

Application

1,1,2-Tris(tert-butoxycarbonyl)hydrazine serves as a stable, bench-ready precursor for the introduction of hydrazino functionality in complex molecule synthesis. Its three Boc groups provide excellent protection and orthogonality, enabling selective deprotection and controlled coupling in multistep sequences. The compound facilitates efficient access to hydrazine-based heterocycles and functionalized scaffolds commonly encountered in medicinal chemistry and API development.

Synthesis

  • Route1
    • null|null
      870-50-8
    • ~%
    • In-stock
      Di-tert-butyl hydrazine-1,2-dicarboxylate|CS-W001467
      16466-61-8
    • In-stock
      1,1,2-Tris(tert-butoxycarbonyl)hydrazine|CS-M3672
      185456-26-2

    References

    • Kisseljova, Ksenija; Tsubrik, Olga; Sillard, Rannar; Maeeorg, Sirje; Maeeorg, Uno Organic Letters, 2006 , vol. 8, # 1 p. 43 - 45
  • Route2
    • null|null
      185456-24-0
    • ~%
    • In-stock
      1,1,2-Tris(tert-butoxycarbonyl)hydrazine|CS-M3672
      185456-26-2

    References

    • Maeeorg, Uno; Grehn, Leif; Ragnarsson, Ulf Angewandte Chemie, 1996 , vol. 108, # 22 p. 2802 - 2803
  • Route3

    References

    • Maeeorg, Uno; Grehn, Leif; Ragnarsson, Ulf Angewandte Chemie, 1996 , vol. 108, # 22 p. 2802 - 2803

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   94.17
  • LogP   3.5983
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   0

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