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CS-W001157 4
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4-Isobutyldihydro-2H-pyran-2,6(3H)-dione

  • CAS No. 185815-59-2

  • Cat. No. CS-0154236
  • Molecule weight170.21
  • Purity≥95%
  • MDL No.MFCD15529750

*For research and further manufacturing use only, not for direct human use.

4-Isobutyldihydro-2H-pyran-2,6(3H)-dione|CS-0154236

Structure of 185815-59-2

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General Information

  • CAS No. 185815-59-2
  • Cat. No. CS-0154236
  • Purity ≥95%
  • MDL No. MFCD15529750
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄O₃
  • Molecular Weight 170.21
  • Synonym(s) 3-Isobutylglutaric anhydride
  • SMILES CC(C)CC1CC(=O)OC(=O)C1

Description

This dihydropyranone features a sterically hindered isobutyl group that enhances stability and solubility in organic media. The conjugated diketone system supports efficient Michael additions and cycloadditions, enabling rapid access to complex heterocyclic scaffolds under mild conditions.

Application

4-Isobutyldihydro-2H-pyran-2,6(3H)-dione serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyranone scaffolds. Its dihydropyranone core exhibits robust bench stability and tolerates a range of functional groups, facilitating downstream transformations such as nucleophilic additions, reductions, and cross-coupling reactions. The isobutyl substituent enhances solubility and aids in purification, making it well-suited for iterative synthesis in medicinal chemistry and natural product derivatization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   1.5123
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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