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CS-W001157 4
Total: USD 88.00

2-Methylpyridin-4-ol

  • CAS No. 18615-86-6

  • Cat. No. CS-W018581
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methylpyridin-4-ol|CS-W018581

Structure of 18615-86-6

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General Information

  • CAS No. 18615-86-6
  • Cat. No. CS-W018581
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇NO
  • Molecular Weight 109.13
  • Synonym(s) 4-Hydroxy-2-methylpyridine
  • SMILES OC1=CC(C)=NC=C1

Description

2-Methylpyridin-4-ol features a pyridine ring bearing a methyl group at the 2-position and a hydroxyl moiety at the 4-position, delivering enhanced solubility and reactivity. This configuration enables efficient incorporation into heterocyclic scaffolds and facilitates metal coordination in catalytic systems. The compound exhibits bench-stable behavior under standard conditions.

Application

2-Methylpyridin-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through electrophilic substitution and transition-metal-catalyzed coupling reactions. Its phenolic hydroxyl group provides a site for derivatization, while the pyridinic nitrogen offers coordination potential. The methyl substituent enhances metabolic stability and modulates electronic properties, contributing to favorable physicochemical profiles. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.09562
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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