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Structure of 18615-86-6
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2-Methylpyridin-4-ol features a pyridine ring bearing a methyl group at the 2-position and a hydroxyl moiety at the 4-position, delivering enhanced solubility and reactivity. This configuration enables efficient incorporation into heterocyclic scaffolds and facilitates metal coordination in catalytic systems. The compound exhibits bench-stable behavior under standard conditions.
2-Methylpyridin-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through electrophilic substitution and transition-metal-catalyzed coupling reactions. Its phenolic hydroxyl group provides a site for derivatization, while the pyridinic nitrogen offers coordination potential. The methyl substituent enhances metabolic stability and modulates electronic properties, contributing to favorable physicochemical profiles. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: