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Structure of 186390-77-2
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6-Nitro-1,2,3,4-tetrahydroisoquinoline features a fused bicyclic scaffold with a nitro group at the C6 position, imparting strong electron-withdrawing character. This structural motif enables direct incorporation into bioactive molecule design, particularly in medicinal chemistry scaffolds requiring modulated electronic properties and enhanced metabolic stability.
6-Nitro-1,2,3,4-tetrahydroisoquinoline serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard reduction and functionalization protocols. Its nitro group facilitates selective transformations such as reductive amination, coupling reactions, and cyclization cascades. The scaffold exhibits good bench stability and compatibility with common protecting groups, making it well-suited for iterative synthetic strategies in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: