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CS-W001157 4
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Dimethyl 2-bromoterephthalate

  • CAS No. 18643-86-2

  • Cat. No. CS-0137245
  • Purity≥97%
  • MDL No.MFCD00060638

*For research and further manufacturing use only, not for direct human use.

Dimethyl 2-bromoterephthalate|CS-0137245

Structure of 18643-86-2

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General Information

  • CAS No. 18643-86-2
  • Cat. No. CS-0137245
  • Purity ≥97%
  • MDL No. MFCD00060638
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉BrO₄
  • Molecular Weight 273.08
  • Synonym(s) O-Bromoterephthalic Acid Dimethyl Ester
  • SMILES O=C(C1=CC=C(C(OC)=O)C=C1Br)OC

Description

Dimethyl 2-bromoterephthalate features a brominated aromatic ring flanked by two ester groups, enabling direct incorporation into polymer backbones via coupling reactions. This electron-deficient diester serves as a key monomer for synthesizing functionalized polyesters and advanced materials with tailored thermal and mechanical properties.

Application

Dimethyl 2-bromoterephthalate serves as a versatile diester building block for the synthesis of functionalized aromatic scaffolds. The bromine substituent enables palladium-catalyzed cross-coupling reactions, including Suzuki and Stille couplings, facilitating the construction of complex biaryl architectures. Its bench-stable nature, combined with excellent functional group tolerance and straightforward purification, makes it well-suited for iterative synthetic sequences in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   2.0223
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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