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Structure of 186590-26-1
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5-Bromo-2,3-difluorophenol delivers a trifunctional aromatic scaffold with orthogonal reactivity. The bromine at C5 enables palladium-catalyzed cross-coupling, while the adjacent difluoro substitution enhances metabolic stability and modulates electron density. This bench-stable phenolic platform integrates readily into bioactive molecule design, offering precise control over lipophilicity and electronic profile in medicinal chemistry applications.
5-Bromo-2,3-difluorophenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct incorporation of bromo- and difluoro-substituted aryl motifs. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient construction of complex heterocycles and biaryl scaffolds. The presence of orthogonal functional groups supports sequential derivatization, making it a practical choice for multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: