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CS-W001157 4
Total: USD 88.00

α-(2-Chloroethyl)benzenemethanol

  • CAS No. 18776-12-0

  • Cat. No. CS-W019837
  • Purity≥98%
  • MDL No.MFCD09878800
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

α-(2-Chloroethyl)benzenemethanol|CS-W019837

Structure of 18776-12-0

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Description

α-(2-Chloroethyl)benzenemethanol features a benzyl alcohol moiety linked to a chloroethyl side chain, enabling direct functionalization in synthetic transformations. This reactive handle facilitates nucleophilic substitution and serves as a key intermediate in pharmaceutical and agrochemical synthesis. The molecule exhibits enhanced stability under standard bench conditions while maintaining high reactivity toward amines and thiols.

Application

α-(2-Chloroethyl)benzenemethanol serves as a versatile bifunctional building block in synthetic organic chemistry, combining a benzylic alcohol with a β-chloroethyl group. This motif enables straightforward derivatization via nucleophilic substitution or elimination reactions, facilitating the construction of heterocyclic scaffolds and functionalized alkyl chains. Its bench-stable nature and compatibility with common protecting group strategies make it a practical choice for iterative synthesis workflows in medicinal chemistry and process development.

General Information

  • CAS No. 18776-12-0
  • Cat. No. CS-W019837
  • Purity ≥98%
  • MDL No. MFCD09878800
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁ClO
  • Molecular Weight None
  • Synonym(s) 3-Chloro-1-phenyl-1-propanol; 3-Chloro-1-phenylpropanol; α-(2-Chloroethyl)benzyl alcohol; 3-Chloro-1-phenylpropan-1-ol
  • SMILES ClCCC(O)C1=CC=CC=C1

Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.3489
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

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