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CS-W001157 4
Total: USD 88.00

2-(2-Methoxyphenoxy)acetic acid

  • CAS No. 1878-85-9

  • Cat. No. CS-0106585
  • Purity≥98%
  • MDL No.MFCD00014352
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-(2-Methoxyphenoxy)acetic acid|CS-0106585

Structure of 1878-85-9

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Description

This compound features a methoxy-substituted phenoxy moiety linked to a carboxylic acid via an acetyl spacer. The electron-donating methoxy group enhances solubility and modulates electronic properties, while the pendant acid enables derivatization or salt formation. Designed for use in synthetic intermediates, this structure integrates readily into bioactive molecule scaffolds requiring polar, aromatic functionality under standard conditions.

Application

2-(2-Methoxyphenoxy)acetic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-methoxyphenyl ether functionality enables efficient coupling reactions, while the carboxylic acid group facilitates derivatization via esterification, amidation, or salt formation. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for use in iterative synthetic sequences and medicinal chemistry campaigns.

General Information

  • CAS No. 1878-85-9
  • Cat. No. CS-0106585
  • Purity ≥98%
  • MDL No. MFCD00014352
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₄
  • Molecular Weight 182.17
  • Synonym(s) Guaiacoxyacetic acid
  • SMILES O=C(O)COC1=CC=CC=C1OC

Computational Chemistry Data

  • TPSA   55.76
  • LogP   1.1586
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

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