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Structure of 188057-35-4
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6-Bromo-2-iodopyridin-3-ol features a pyridin-3-ol core bearing bromo and iodo substituents at the 6- and 2-positions, respectively. This electron-deficient heterocycle enables direct functionalization in cross-coupling reactions. The phenolic hydroxyl group offers a site for derivatization or metal coordination. Bench-stable under standard conditions, this compound serves as a key building block in medicinal chemistry and materials synthesis.
6-Bromo-2-iodopyridin-3-ol serves as a versatile building block for late-stage functionalization and cross-coupling reactions in medicinal chemistry. The molecule combines bromo and iodo substituents at electronically distinct positions on the pyridine core, enabling sequential or selective Pd-catalyzed transformations. Its phenolic hydroxyl group provides a handle for derivatization or metal complexation, while the halogenated framework ensures compatibility with standard Suzuki, Stille, and Negishi coupling protocols. Bench-stable and readily purified by crystallization, it functions reliably in multi-step synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: