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CS-W001157 4
Total: USD 88.00

(E)-1,2-Bis(4-bromophenyl)ethene

  • CAS No. 18869-30-2

  • Cat. No. CS-0158505
  • Purity≥96%
  • MDL No.MFCD00448009

*For research and further manufacturing use only, not for direct human use.

(E)-1,2-Bis(4-bromophenyl)ethene|CS-0158505

Structure of 18869-30-2

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General Information

  • CAS No. 18869-30-2
  • Cat. No. CS-0158505
  • Purity ≥96%
  • MDL No. MFCD00448009
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₀Br₂
  • Molecular Weight 338.04
  • Synonym(s) trans-4,4'-Dibromostilbene
  • SMILES C(=C\C1=CC=C(C=C1)Br)/C2=CC=C(C=C2)Br

Application

(E)-1,2-Bis(4-bromophenyl)ethene serves as a versatile bisaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds under standard Suzuki-Miyaura conditions. Its trans-stereochemistry and bench-stable nature facilitate reproducible coupling with boronic acids, while the bromo substituents offer orthogonal functionalization potential. This compound functions reliably in the synthesis of conjugated materials and advanced pharmaceutical intermediates.

Synthesis

  • Route1

    References

    • CHENG, Chien-Hong; Hsu, He-Pei; Chou, Ho-Hsiu; Chen, Yu-Han; Chen, Yi-Hsiang Patent: US2013/41153 A1, 2013 ; Location in patent: Paragraph 0045; 0046; 0047; 0048 ;
  • Route2

    References

    • Talele, Harish R.; Chaudhary, Anju R.; Patel, Parthiv R.; Bedekar, Ashutosh V. Arkivoc, 2011 , vol. 2011, # 9 p. 15 - 37
  • Route3

    References

    • US7758972 B2, ; Page/Page column 77 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.382
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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