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Structure of 188781-08-0
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Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate features a pyrimidine core with orthogonal reactive handles: a chloro group at C2 enabling nucleophilic substitution and an ester at C5 for selective derivatization. The methyl substituent at C4 enhances electronic stabilization, while the ethyl ester facilitates purification and downstream transformations under standard conditions. This compound serves as a key scaffold in heterocyclic synthesis.
Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of pyrimidine-based scaffolds. The chloro group at C2 facilitates nucleophilic substitution reactions, while the ester function supports further derivatization. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: