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Structure of 1889221-15-1
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This boronate moiety features a 6-methyl-5-(trifluoromethyl)pyridin-3-yl scaffold, combining electron-deficient heteroaromaticity with enhanced stability. The trifluoromethyl group imparts strong lipophilicity and metabolic resistance, while the boronic acid enables efficient Suzuki-Miyaura cross-coupling under standard conditions. This bench-stable reagent streamlines access to complex pyridine-based architectures in medicinal chemistry and materials science.
(6-Methyl-5-(trifluoromethyl)pyridin-3-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its trifluoromethyl and methyl substituents enhance metabolic stability and modulate electronic properties, while the boronic acid group offers excellent bench stability and compatibility with diverse reaction conditions. Ideal for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds, it facilitates rapid diversification through reliable, high-yielding couplings.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: