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Structure of 188937-16-8
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Thiazol-2-yl-acetic acid features a thiazole ring linked to a carboxylic acid group, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key pharmacophore in kinase inhibitors and antimicrobial agents. The acidic proton enables salt formation, improving formulation compatibility.
Thiazol-2-yl-acetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of thiazole-containing bioactive molecules. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the thiazole ring provides metabolic stability and enhanced target affinity. The molecule exhibits good bench stability and compatibility with standard purification methods, making it suitable for scalable synthesis of API intermediates and heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: