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CS-W001157 4
Total: USD 88.00

N-Boc-Morpholine-2-carboxylic acid

  • CAS No. 189321-66-2

  • Cat. No. CS-W018922
  • Purity≥95%
  • MDL No.MFCD01321006
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-Boc-Morpholine-2-carboxylic acid|CS-W018922

Structure of 189321-66-2

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Description

N-Boc-Morpholine-2-carboxylic acid features a morpholine ring bearing a Boc-protected carboxylic acid at the 2-position, enabling stable incorporation into peptide and small-molecule syntheses. The protected functionality facilitates selective deprotection under mild acidic conditions, streamlining access to bioactive intermediates. This bench-stable derivative supports efficient coupling reactions in diverse chemical contexts.

Application

N-Boc-Morpholine-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of morpholine-containing scaffolds via standard deprotection and coupling protocols. Its Boc group provides excellent bench stability and orthogonal handling in multi-step syntheses, while the carboxylic acid functionality facilitates efficient amide bond formation under common coupling conditions. This compound functions reliably in peptide and heterocyclic library construction, offering predictable reactivity and straightforward purification.

General Information

  • CAS No. 189321-66-2
  • Cat. No. CS-W018922
  • Purity ≥95%
  • MDL No. MFCD01321006
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇NO₅
  • Molecular Weight 231.25
  • Synonym(s) 4-N-Boc-3-morpholinecarboxylic acid
  • SMILES O=C(C1CN(C(OC(C)(C)C)=O)CCO1)O

Computational Chemistry Data

  • TPSA   76.07
  • LogP   0.7069
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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