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1-(2-Bromophenyl)naphthalene

  • CAS No. 18937-92-3

  • Cat. No. CS-0504445
  • Purity≥98%
  • MDL No.MFCD18415511

*For research and further manufacturing use only, not for direct human use.

1-(2-Bromophenyl)naphthalene|CS-0504445

Structure of 18937-92-3

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General Information

  • CAS No. 18937-92-3
  • Cat. No. CS-0504445
  • Purity ≥98%
  • MDL No. MFCD18415511
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₁Br
  • Molecular Weight 283.16
  • Synonym(s) 1-(2-bromophenyl)naphthale
  • SMILES BrC1=CC=CC=C1C2=C3C=CC=CC3=CC=C2

Description

Dodecyl aldehyde is used as a fragrance agent. It is used as a common ingredient in perfumery. It's end applications include soap, detergent, beauty care product, household product.

Application

1-(2-Bromophenyl)naphthalene serves as a versatile building block for Suzuki-Miyaura and Negishi coupling reactions, enabling the construction of biaryl scaffolds under standard palladium-catalyzed conditions. The bromo group exhibits high reactivity with minimal side-product formation, while the naphthalene core provides structural rigidity and enhanced stability during purification. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • CANON KABUSHIKI KAISHA; NISHIDE, Yosuke; MIYASHITA, Hirokazu; KAMATANI, Jun; SAITOH, Akihito Patent: WO2011/96272 A1, 2011 ; Location in patent: Page/Page column 37-38 ;
  • Route2

    References

    • Wegner, Hermann A.; Scott, Lawrence T.; De Meijere, Armin Journal of Organic Chemistry, 2003 , vol. 68, # 3 p. 883 - 887
  • Route3

    References

    • Wang, Tein-Fu; Lin, Ching-Lung; Chen, Chih-Neng; Wang, Tan-Ching Journal of the Chinese Chemical Society, 2007 , vol. 54, # 3 p. 811 - 816

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   5.2693
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   1

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