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CS-W001157 4
Total: USD 88.00

(2-Bromophenyl)methanol

  • CAS No. 18982-54-2

  • Cat. No. CS-W008828
  • Molecule weight187.04
  • Purity≥98%
  • MDL No.MFCD00004600

*For research and further manufacturing use only, not for direct human use.

(2-Bromophenyl)methanol|CS-W008828

Structure of 18982-54-2

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General Information

  • CAS No. 18982-54-2
  • Cat. No. CS-W008828
  • Purity ≥98%
  • MDL No. MFCD00004600
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrO
  • Molecular Weight 187.04
  • Synonym(s) o-bromobenzyl alcohol
  • SMILES BrC1=CC=CC=C1CO

Description

2-Bromobenzyl alcohol was used in microwave assisted palladium-catalyzed synthesis of phthalides. It was also used in the synthesis of 1-hydroxy-3(1H)-l,2-benzoboroxole.

Application

(2-Bromophenyl)methanol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized aryl scaffolds. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the benzylic alcohol group supports oxidation to aldehydes or esterification for further derivatization. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it valuable for medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Bozinovic, Nina; Opsenica, Igor; Solaja, Bogdan A. Synlett, 2013 , vol. 24, # 1 p. 49 - 52
  • Route2
    • null|null
      59184-20-2
    • ~10%
    • In-stock
      (2-Bromophenyl)methanol|CS-W008828
      18982-54-2

    References

    • Shirini, Farhad; Khaligh, Nader Ghaffari; Akbari-Dadamahaleh, Somayeh Journal of Molecular Catalysis A: Chemical, 2012 , vol. 365, p. 15 - 23
  • Route3

    References

    • Yamakawa, Tomio; Masaki, Mitsuo; Nohira, Hiroyuki Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 9 p. 2730 - 2734

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H412
Precautionary Statements : P264-P270-P273-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.9414
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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