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Structure of 190783-99-4
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1-Methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester features a reactive pyrrolidinone core with a methyl ester handle, enabling direct incorporation into peptide couplings. The electron-deficient carbonyl at C5 enhances nucleophilic attack efficiency, while the N-methyl group improves solubility and metabolic stability. This scaffold serves as a key building block in bioactive molecule synthesis.
1-Methyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester serves as a versatile building block in synthetic organic chemistry, enabling efficient access to pyrrolidine-based heterocycles and bioactive scaffolds. Its α,β-unsaturated carbonyl motif facilitates Michael additions, while the ester functionality supports subsequent hydrolysis or coupling reactions. Bench-stable and readily purified by standard chromatographic methods, it functions effectively in both small-molecule synthesis and medicinal chemistry campaigns requiring robust, functionalized nitrogen-containing frameworks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: