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Structure of 190788-60-4
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This boronate ester features a methoxy-substituted phenyl group coupled with a tetramethyl-1,3,2-dioxaborolane ring, delivering enhanced stability and solubility in organic media. The electron-rich aryl moiety facilitates efficient coupling in Suzuki-Miyaura reactions, while the sterically protected boron center ensures minimal hydrolysis under standard conditions. Ideal for late-stage functionalization and modular synthesis in medicinal chemistry workflows.
2-(2-Methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its ortho-methoxy substitution enhances regioselectivity in heterocyclic coupling and improves solubility in common organic solvents. The tetramethyl-substituted dioxaborolane core ensures excellent stability and ease of purification, making it ideal for iterative synthesis of biaryl scaffolds and complex pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P341-P312-P330-P363-P501
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Lot numbers can be found on the outside label of a product: